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Invisible changes in our cells may shape health and disease

DNA image imposed on layer of cells showing somatic mosaicism
Changes that switch genes on or off without altering DNA escape today’s tests yet may help drive cancer and other diseases.

News Releases

Blood donation in airport hanger in Ukraine during the ongoing war. Faces are blurred to protect identities.

Ukraine maintains self-sufficient blood system despite war

Facing a 40% higher demand and a loss of donors from population displacements, Ukraine’s blood system adapted to meet military and civilian needs.
scientists work in the Institute for Protein Design's dry lab

Researchers achieve major advance in protein design

A new open-source generative model surpasses its predecessors by using biomolecular reasoning to solve difficult design problems.
illustration of molecular proteins that act as scissors at a molecular level

Molecular ‘scissors’ open path to new therapies

In two studies published in Nature, computationally designed enzymes cut disease-related proteins at precise sites.
Dr. Kristina Adams Waldorf looks at a placental tissue specimen on a slide

Flu in pregnancy forces the placenta into costly defense

The placenta pays a price for fighting influenza, researchers say, a finding that adds urgency to vaccination.
the pronuclear injection of the DNA Typewriter into a fertilized mouse egg

DNA Typewriter records cells’ history in early mouse embryo

Inserted into a fertilized mouse egg genome, the tape then tracked the lineage of 1.3 million embryonic cells up to late organ development.
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picture of Nathan Hyun and Tim Griffis

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