protein design

This twisting protein structure dreamed up by a machine-learning algorithm.
December 1, 2021

Deep learning dreams up new protein structures

A neural network trained exclusively to predict protein shapes can also generate new ones.

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Artificial intelligence generated structure of 3D human interleukin-12 bound to receptor
July 15, 2021

Accurate protein structure prediction now accessible to all

New artificial intelligence software can compute protein structures in 10 minutes.

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Custom-designed protein nanoparticle for HIV vaccine
August 4, 2020

HIV vaccine design strategy holds promise for COVID-19

Tailored vaccines developed at UW Medicine enable a more targeted immune response against viruses.

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A 3D printed lung air sac
January 3, 2020

UW Medicine-linked achievements make 2019 top lists

Cystic fibrosis treatment, Denisovan anatomy, and 3D organ printing were among the highlighted pursuits of last year.

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Models of computer-designed proteins
April 16, 2019

Protein design may solve vexing problems in medicine

The Institute for Protein Design will become an innovation hub for new therapeutics for a variety of common, serious diseases. It will also engineer new nanomaterials for industry.

This conceptual art "Illuminating the energy landscape"
December 14, 2017

Computational strategies overcome obstacles in peptide drug development

Approaches developed at the UW Institute of Protein Design might help researchers in the design of midsize drug compounds.

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illustration of synthetic nucleocapsids
December 13, 2017

Synthetic protein packages its own genetic material and evolves

Computationally designed protein assemblies, which display functions associated with living things, may pose ways to transport therapeutic cargos into cells without using viruses as vehicles.

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picture of a computer-generated protein molecule
September 27, 2017

Soundbites: David Baker discusses mini-protein finding

(Downloadable video soundbites and lab b-roll)  Scientist David Baker discusses creating proteins custom tailored to specific therapeutic targets.

Artist impression of designed mini-protein binders
September 27, 2017

Mini-protein rapid design opens way to new class of drugs

Scientists have created a way to generate thousands of different mini-protein binders as possible drug candidates.  

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mini proteins targeting flu virus
September 27, 2017

Drawing of computer-designed mini-proteins targeting flu virus

Artist impression of designed mini-protein binders targeting Influenza hemagglutinin to effectively bind and neutralize the virus. 

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