Institute for Protein Design

Traces of protein changes that have occurred over millions of years of evolution have allowed scientists to quickly decipher the 3-D shape of hundreds of proteins.  Previously, these structures had remained a long-standing puzzle.

Scientists at the University of Washington in Seattle have deciphered key rules that govern how proteins form pocket-like structures essential to many protein functions.

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Scientists at the University of Washington’s Institute for Protein Design have shown it is possible to create small, hyperstable peptides that could provide the basis for developing powerful new drugs and diagnostic tests. 

Gamers playing the popular online puzzle game Foldit triumphed over scientists, college students and computer algorithms in a contest to identify a particular protein molecule’s shape. 

GeekWire reports the news that biochemists at th

A small protein molecule, engineered through computer design, protects against diverse strains of influenza in mice. Its preventive and therapeutic power does not depend on the animals’ own immune response to viral infection. 

The potential of modular design for brand new proteins that do not yet exist in the natural world is explored Dec. 16 in the journal Nature.

A team at the University of Washington is developing an enzyme aimed at enabling people with Celiac disease to safely eat foods with gluten.


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