These computer-designed proteins, which did not previously exist in nature, combine the stability and bioavailability of small molecule drugs with the specificity and potency of larger biologics. They would not require refrigeration, and they l
When a protein folds correctly, it spurs a biological process in a cell -- one of many that enable the human body to live. Our bodies have about 100,000 distinct proteins, built from strings of amino acids, and each protein has a job to do.
Traces of protein changes that have occurred over millions of years of evolution have allowed scientists to quickly decipher the 3-D shape of hundreds of proteins. Previously, these structures had remained a long-standing puzzle.
Scientists at the University of Washington’s Institute for Protein Design have shown it is possible to create small, hyperstable peptides that could provide the basis for developing powerful new drugs and diagnostic tests.