Institute for Protein Design

David Baker talking to researcher
January 9, 2019

Interleukin-2 (IL-2) is a molecule that amps up immune cells to fight off infections. While it is effective, the problem with IL-2 is that it causes a lot of toxicity in patients.

January 10, 2019

Scientists at UW Medicine’s Institute for Protein Design  have created a new protein that mimics the action of a key immune regulatory protein, interleukin 2 (IL-2).  IL-2 is a potent anticanc

December 19, 2018

Proteins have now been designed in the lab to zip together in much the same way that  DNA molecules zip up to form a double helix.  The technique, whose development was led by University of Washington School of Medicine scientists, could enable

November 8, 2018

For the first time, scientists have created from scratch self-assembling protein filaments built from identical protein subunits that snap together spontaneously to form long, helical, thread-like structures.

October 29, 2018

For the first time scientists have successfully designed non-local beta-sheet proteins from scratch.

September 13, 2018

For the first time, scientists have created, entirely from scratch,  a protein capable of binding to a small target molecule.

picture of David Baker
April 4, 2018

The Institute for Protein Design at the University of Washington School of Medicine has been awarded $11.3 million from the Open Phi

March 1, 2018

In the living world, transmembrane proteins are found embedded in the membrane of all cells and cellular organelles. They are essential for them to function normally.

December 26, 2017

Two decades ago, the notion of building custom proteins and correctly predicting their structure was a dream.

December 13, 2017

Protein assemblies, designed and built from scratch to carry molecular cargo, are advancing both synthetic life research and engineering efforts for targeted drug delivery.

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