How melatonin regulates the body's sleep-wake cycle

March 13, 2019

How melatonin regulates the body's sleep-wake cycle

As we recover from the effects of daylight-saving time, some may take a melatonin supplement at supper to help with sleep. Melatonin is a hormone that your pineal gland, part of your circadian clock in the brain, naturally produces and releases throughout the night. Evening peaks and morning drops in melatonin play a role in regulating sleep-wake cycles.

The lab of Bertil Hille, physiology and biophysics professor at the University of Washington School of Medicine, is studying the body's rhythmic secretion of and response to melatonin. Understanding these patterns could improve treatment of sleep disorders, seasonal affective reactions to short winter days, and loss of attention and productivity due to jet lag, time switches or working the night shift.  He explains the research in the video below.

Downloadable media assets:

Category: 
YouTube

Terms of appropriate usage of file downloads

  • News reporters and news organizations may freely republish and distribute videos, still images and audio files produced by UW Medicine and the University of Washington School of Medicine.
  • Works must be attributed/credited appropriately (for example, “UW Medicine” – as denoted in the file) and must not be used for commercial purposes.
  • These visual and audio files may not be used to exploit or misrepresent UW Medicine or the University of Washington.
  • UW Medicine often licenses still images from Thinkstock but cannot grant republishing rights. You may not republish single image files credited to Thinkstock.
  • Logos of UW Medicine and University of Washington Health Sciences schools may not be republished without explicit permission. Contact us by phone or email: 206.543.3620 or mediarelations@uw.edu